Search on: PEPSIN A 
Descriptors Found: 1
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Descriptor English:   Pepsin A 
Descriptor Spanish:   Pepsina A 
Descriptor Portuguese:   Pepsina A 
Synonyms English:   Pepsin 1
Pepsin 3
Pepsin  
Tree Number:   D08.811.277.656.074.500.700
D08.811.277.656.300.048.700
Definition English:   Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice. 
Indexing Annotation English:   /biosyn /physiol permitted
Pharmacological Action:   Gastrointestinal Agents
 
History Note English:   91; was PEPSIN 1964-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   29296 
Unique Identifier:   D010434 

Occurrence in VHL:
 

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